منابع مشابه
John Cunningham virus T-antigen expression in anal carcinoma.
BACKGROUND Anal carcinoma is thought to be driven by human papillomavirus (HPV) infection through interrupting function of cell regulatory proteins such as p53 and pRb. John Cunningham virus (JCV) expresses a T-antigen that causes malignant transformation through development of aneuploidy and interaction with some of the same regulatory proteins as HPV. JCV T-antigen is present in brain, gastri...
متن کاملCunningham 31_8
Signalling via the insulin-like growth factor-I receptor (IGF-IR) has been associated with resistance to antiepidermal growth factor receptor (EGFR) and human epidermal growth factor receptor-2 (HER-2)-based therapies in the experimental system, but the coexpression and clinical significance of the IGF-IR, EGFR and HER-2 in cancer patients remains unclear. IGF-IR, EGFR, and HER-2 status was ass...
متن کاملOn Cunningham Chains
Let q be a prime with primitive root 2. We show that (a) if (pi) q−2 i=0 is a sequence of primes such that pi = 2pi−1 + 1 for all 1 ≤ i ≤ q − 2, then q divides p0 + 1 or p0 ∈ {2, 3, 5} and (b) if (pi) q−2 i=0 is a sequence of primes such that pi = 2pi−1 − 1 for all 1 ≤ i ≤ q − 2, then q divides p0 − 1 or p0 ∈ {2, 3}.
متن کاملRoland Henning , Robert J . Milner , Konrad Reske , Bruce a . Cunningham , and Gerald M
Detergent and papain solubilized murine histocompatibility (H-2) antigens have been compared by gel exclusion chromatography, ultracentrifugation, sodium dodecyl sulfate-polyacrylamide gel electrophoresis, and aminoacid sequence analysis. From these data, we propose a molecular model for the H-2 antigens that includes the size and arrangement of the subunits on the cell surface and in solution,...
متن کاملBarbara Shinn-Cunningham
encoded in the brain. Somehow, I now find myself a neuroscientist. But I still suffer from gaps in my knowledge. That is why I like collaborating. of their cells carried the change. Moreover, the cells had their own mind on how to repair the change, with a quarter of them using endogenous templates, while cuts in off-target locations were also observed. The high likelihood of unwanted reactions...
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ژورنال
عنوان ژورنال: Nature
سال: 1935
ISSN: 0028-0836,1476-4687
DOI: 10.1038/136013a0